Alcohol Dehydrogenase (ADH) (AA 1-325) Protein

Catalog No. ABIN935073

Product Details

Target: Alcohol Dehydrogenase (ADH)

Protein Type: Recombinant

Protein Characteristics: AA 1-325

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE EPVVLALAEK YGRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV PMLTVDGKRV PRDAGHPLYP FNDPY

Characteristics: Purified recombinant Human Alcohol dehydrogenase protein
Expression System: E.coli

Purity: > 90 % pure

Application Details

Application Notes: Alcohol dehydrogenase protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 50 mM NaCl and 10 % glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: Alcohol Dehydrogenase (ADH)

Alternative Name: Alcohol dehydrogenase (ADH Products)

Synonyms: ADH Protein, ALCOHOL DEHYDROGENASE Protein, ARABIDOPSIS THALIANA ALCOHOL DEHYDROGENASE Protein, ATADH Protein, ATADH1 Protein, F22K20.19 Protein, F22K20_19 Protein, alcohol dehydrogenase 1 Protein, 2610201A18Rik Protein, Akr1a4 Protein, ALR1 Protein, Adh Protein, Adh1a Protein, Adh1c Protein, aldo-keto reductase family 1 member A1 Protein, alcohol dehydrogenase 1 Protein, aldo-keto reductase family 1, member A1 (aldehyde reductase) Protein, alcohol dehydrogenase 1 (class I) Protein, AKR1A1 Protein, ADH1 Protein, Akr1a1 Protein, Adh1 Protein

Background: Alcohol dehydrogenase [NADP+] (AKR1A1) is a member of the aldo/keto reductase superfamily and catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. This protein is closely related (65 % identity) to aldose reductase, an enzyme involved in the pathogenesis of some diabetic and galactosemic complications. It plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Recombinant human Alcohol dehydrogenase was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: ALDR1 protein, Alcohol dehydrogenase [NADP+] Alcohol dehydrogenase protein, Aldehyde reductase protein, AKR1A1 protein, ARM protein, aldo-keto reductase family 1 member A1 (aldehyde reductase)., ALR protein, DD3 protein

Molecular Weight: 36.5 kDa (325 AA)