HDGF Protein (AA 1-100)

Catalog No. ABIN935063

Product Details

Target: HDGF (Hepatoma-Derived Growth Factor (HDGF))

Protein Type: Recombinant

Protein Characteristics: AA 1-100

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY

Characteristics: Purified recombinant Human HDGF protein
Expression System: E.coli

Purity: > 95 % pure

Application Details

Application Notes: HDGF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0 mM DTT, 10 % glycerol, and 0 mM EDTA.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: HDGF (Hepatoma-Derived Growth Factor (HDGF))

Alternative Name: HDGF (HDGF Products)

Synonyms: HMG1L2 Protein, hmg1l2 Protein, HDGF Protein, DKFZp459H185 Protein, AI118077 Protein, D3Ertd299e Protein, heparin binding growth factor Protein, hepatoma-derived growth factor Protein, hepatoma-derived growth factor (high-mobility group protein 1-like) Protein, heparin binding growth factor L homeolog Protein, hepatoma-derived growth factor-like Protein, HDGF Protein, hdgf Protein, Hdgf Protein, hdgf.L Protein, LOC100357981 Protein

Background: Hepatoma-derived growth factor isoform a, also known as HDGF, belongs to the hepatoma-derived growth factor family. HDGF was originally identified as a secreted mitogen from the human hepatoma cell line Huh-7. This nuclear targeted vascular smooth muscle cell mitogen is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. Recombinant human HDGF was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: HMG1L2 protein, , High mobility group protein 1 like 2 protein, Hepatoma-derived growth factor isoform a Hepatoma derived growth factor protein

Molecular Weight: 11.5 kDa (100 AA)

Pathways: ER-Nucleus Signaling