TCL1A Protein (AA 1-114)
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- Target See all TCL1A Proteins
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-114
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD
- Characteristics
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Purified recombinant Human TCL1 A protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 90 % pure
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T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-114) protein (GST tag)
TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 7-102) protein (GST tag)TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 61-114) protein (GST tag)TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TCL1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
T-Cell Leukemia/lymphoma 1A (TCL1A) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TCL1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- TCL1A protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 50 mM Tris-HCl buffer, pH 7.5, containing 10 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Alternative Name
- TCL1A (TCL1A Products)
- Synonyms
- TCL1A Protein, Tcl1a Protein, TCL1 Protein, Tcl1 Protein, T-cell leukemia/lymphoma 1A Protein, T cell lymphoma breakpoint 1 Protein, TCL1A Protein, Tcl1 Protein, Tcl1a Protein
- Background
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TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: TCL 1 protein protein, T cell leukemia 1 protein, TCLA-1 protein, TCL1A, TCLA 1, TCL-1 protein, TCL1A protein, TCL1 oncogene protein, P14 TCL1 protein protein, protein p14TCL1 protein, TCL1 PEN protein, TCLA 1 protein, Oncogene TCL1 protein, T-cell leukemia/lymphoma 1A anti TCL1A protein, T cell lymphoma 1A protein, TCL1A., TCL1 protein, T cell lymphoma 1 protein, P14 TCL1 protein, TCLA-1 - Molecular Weight
- 13.4 kDa (114 AA)
- Pathways
- Stem Cell Maintenance
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