TBCA Protein (AA 1-108)
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- Target See all TBCA Proteins
- TBCA (Tubulin Folding Cofactor A (TBCA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-108
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA
- Characteristics
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Purified recombinant Human TBCA protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
- Top Product
- Discover our top product TBCA Protein
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- Application Notes
- TBCA protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 1 mM DTT, and 10 % glycerol.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- TBCA (Tubulin Folding Cofactor A (TBCA))
- Alternative Name
- TBCA (TBCA Products)
- Synonyms
- Tbca13 Protein, CFA Protein, tbca Protein, zgc:56262 Protein, tubulin cofactor A Protein, tubulin folding cofactor A Protein, tubulin folding cofactor A S homeolog Protein, tubulin cofactor a Protein, Tbca Protein, TBCA Protein, tbca.S Protein, tbca Protein
- Background
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Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. Recombinant human TBCA protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Tubulin cofactor a., Co chaperonin associated with a & b tubulin protein, Tubulin folding cofactor A protein, Cofactor A protein, chaperonin cofactor a protein, TCP1 chaperonin cofactor A protein, TBCA protein, tubulin specific chaperone a protein, Tubulin folding cofactor A CFA protein - Molecular Weight
- 12.8 kDa (108 AA)
- Pathways
- SARS-CoV-2 Protein Interactome
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