CBR1 Protein (AA 1-277)

Catalog No. ABIN935034

Product Details

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Protein Type: Recombinant

Protein Characteristics: AA 1-277

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW

Characteristics: Purified recombinant Human CBR1 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: CBR1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.5, containing 10 % glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: CBR1 (CBR1 Products)

Synonyms: LOC100222525 Protein, MGC131152 Protein, CBR Protein, SDR21C1 Protein, hCBR1 Protein, 9-KPR Protein, AW261796 Protein, CR Protein, Cbr Protein, carbonyl reductase 1 Protein, carbonyl reductase [NADPH] 1 Protein, carbonyl reductase 1 S homeolog Protein, carbonyl reductase Protein, cbr1 Protein, CBR1 Protein, LOC100222525 Protein, cbr1.S Protein, Smp_033530.3 Protein, LOC610164 Protein, Cbr1 Protein

Background: CBR1 (Carbonyl reductase 1) is one of several monomeric NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. CBR1 is widely distributed in human tissues. CBR1 metabolizes many toxic environmental quinones and pharmacologically relevant substrates such as the anticancer doxorubicin. CBR1 can also convert prostaglandin E2 to prostaglandin F2-alpha. Recombinant human CBR1 protein was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Carbonyl reductase 1 15 hydroxyprostaglandin dehydrogenase [NADP+] protein, CBR1 protein, CBR 1, Carbonyl reductase [NADPH] 1.CBR 1 protein, CBR protein, hCBR1 protein, SDR21C1 protein, Prostaglandin E(2) 9 reductase., NADPH dependent carbonyl reductase 1 protein, CBR-1, CRN protein, Carbonyl reductase 1 protein, CBR1, Prostaglandin 9 ketoreductase protein, CBR 1 protein, CBR-1 protein

Molecular Weight: 30 kDa (277 AA)