HSC70 Interacting Protein HIP Protein (AA 1-369)

Catalog No. ABIN935011

Product Details

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Protein Type: Recombinant

Protein Characteristics: AA 1-369

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRAQK IAEHRRKYER KREEREIKER IERVKKAREE HERAQREEEA RRQSGAQYGS FPGGFPGGMP GNFPGGMPGM GGGMPGMAGM PGLNEILSDP EVLAAMQDPE VMVAFQDVAQ NPANMSKYQS NPKVMNLISK LSAKFGGQA

Characteristics: Purified recombinant Human Hip/ST13 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 90 % pure

Endotoxin Level: < 1.0 EU per µg of protein (determined by LAL method)

Application Details

Application Notes: Hip/ST13 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, 0.1 M NaCl, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Alternative Name: Hip/ST13 (ST13 Products)

Synonyms: CG32789 Protein, Dmel\\CG32789 Protein, anon-EST:fe1A9 Protein, 1110007I03Rik Protein, 3110002K08Rik Protein, AW555194 Protein, HIP Protein, HOP Protein, HSPABP Protein, HSPABP1 Protein, PRO0786 Protein, SNC6 Protein, p48 Protein, AAG2 Protein, FAM10A1 Protein, FAM10A4 Protein, P48 Protein, Hsc/Hsp70-interacting protein Protein, suppression of tumorigenicity 13 Protein, ST13, Hsp70 interacting protein Protein, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) Protein, HIP Protein, St13 Protein, ST13 Protein

Background: Hip (Hsc70-interacting protein), also known as ST13, is a co-chaperone to the major heat shock proteins, Hsp70 and Hsp90, and appears in early receptor complexes. Through mutual binding to both Hsp70 and Hsp90, Hip functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. Also, Hip has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. Recombinant human Hip was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Hip/ST 13, Hip/ST13, Hsc70-interacting protein protein, HOP protein, Hip/ST 13 protein, FAM10A1 protein, ST13 protein, SNC6 protein, Hip/ST-13 protein, Hip/ST-13, Hsc70-interacting protein

Molecular Weight: 41.3 kDa (369 AA)