Glutaredoxin 1 Protein (GRX1) (AA 1-106)

Catalog No. ABIN935008

Product Details

Target: Glutaredoxin 1 (GRX1)

Protein Type: Recombinant

Protein Characteristics: AA 1-106

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MAQEFVNCKI QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ

Characteristics: Purified recombinant Human Glutaredoxin 1 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: Glutaredoxin-1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: Glutaredoxin 1 (GRX1)

Alternative Name: Glutaredoxin 1 (GRX1 Products)

Synonyms: Glrx1 Protein, Grx Protein, grx Protein, wu:fc38f02 Protein, zgc:103707 Protein, GLRXL Protein, Grx1 Protein, TTase Protein, C86710 Protein, D13Wsu156e Protein, grx1 Protein, GLRX Protein, GRX Protein, GRX1 Protein, GLRX1 Protein, TTF Protein, glrx Protein, glutaredoxin Protein, glutaredoxin (thioltransferase) Protein, glutaredoxin Grx1 Protein, NrdH-redoxin Protein, Uncharacterized monothiol glutaredoxin F10D7.3 Protein, glutaredoxin-1 (Grx1) Protein, temporal expression: late Protein, glutaredoxin L homeolog Protein, Glrx Protein, glrx Protein, GLRX Protein, grx1 Protein, AF_RS07750 Protein, F10D7.3 Protein, AFUA_1G06100 Protein, NT01EI_2528 Protein, O2L Protein, glrx.L Protein

Target Type: Viral Protein

Background: Glutaredoxin(GRX), also known as thioltransferase, is a member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Mammalian Glutaredoxin is known to have two isoforms, GRX1 and GRX2. GRX1 is a cytosolic protein, whereas GRX2 is localized both in the mitochondria and nucleus. Glutaredoxin-1 may be involved in a various cellular events such as signal transduction, stress response, and metabolic regulation by regulating the redox status of cellular proteins. Recombinant human Glutaredoxin1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: TTase-1 protein, Glutaredoxin protein, GLRX protein, TTase 1 protein, Glutaredoxin-1, Glutaredoxin 1, Glutaredoxin 1 protein, Ttase protein, GRX protein, GRX1 protein, MGC117407 protein, Glutaredoxin1, Grx 1 protein, Thioltransferase protein, Glrx1 protein, Thioltransferase 1 protein, Glutaredoxin-1 protein, Thioltransferase-1 protein, Thioltransferase1 protein, TTase1., Glutaredoxin1 protein

Molecular Weight: 11.7 kDa (106 AA)

Pathways: Cell RedoxHomeostasis