HSPE1 Protein (AA 1-102)

Catalog No. ABIN934958

Product Details

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Protein Type: Recombinant

Protein Characteristics: AA 1-102

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD

Characteristics: Purified recombinant Human HSP10 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: HSP10 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris, pH 8.0, containg 50 mM NaCl.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Alternative Name: HSP10 (HSPE1 Products)

Background: Heat shock protein (HSP) 10 is a member of the highly conserved group of molecular chaperons, which are necessary for efficient folding of many proteins in normal and stress conditions and have been implicated in several human diseases. HSP10 is the ~10kD mammalian equivalent to GroES of E. coli. The function of Hsp10 is to bind Hsp60 (also known as chaperonin-60), in the presence of ATP, thereby promoting a conformational change in Hsp60 and enclosing the protein substrate within the complex. ATP hydrolysis by Hsp60 destabilizes the Hsp60/ Hsp10 complex, allowing it to dissociate and release the substrate protein. Recombinant human HSP10 was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: HSP-10, HSP10 protein, Cpn 10 protein, HSPE1 protein, 10 kDa heat shock protein mitochondrial protein, Heat shock 10kD protein 1 protein, CPN10 protein, Heat shock 10kDa protein 1 chaperonin 10 protein, HSP 10 protein, HSP-10 protein, Heat shock 10kDa protein 1 protein, HSP 10 protein, HSP10 protein, , HSP10, Heat shock 10kD protein 1 chaperonin 10 protein, HSP 10, Early pregnancy factor protein, Heat shock protein 10 10 kDa chaperonin protein, Chaperonin 10 protein, Heat shock protein 10 protein, HSPE 1 protein, GroES protein, EPF protein

Molecular Weight: 10 kDa (102 AA)

Pathways: Positive Regulation of Endopeptidase Activity