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YWHAE Protein (AA 1-255)

YWHAE Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Catalog No. ABIN934949
  • Target See all YWHAE Proteins
    YWHAE (14-3-3 epsilon (YWHAE))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-255
    Origin
    • 8
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Sequence
    MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK NVIGARRASW RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI LDVLDKHLIP AANTGESKVF YYKMKGDYHR YLAEFATGND RKEAAENSLV AYKAASDIAM TELPPTHPIR LGLALNFSVF YYEILNSPDR ACRLAKAAFD DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE EQNKEALQDV EDENQ
    Characteristics
    Purified recombinant Human 14.3.3 epsilon protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
    Purity
    > 95 % pure
    Top Product
    Discover our top product YWHAE Protein
  • Application Notes
    14.3.3 epsilon protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Supplied as a liquid in 20 mM Tris, pH 7.5.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
    Storage Comment
    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target
    YWHAE (14-3-3 epsilon (YWHAE))
    Alternative Name
    14.3.3 epsilon (YWHAE Products)
    Background
    The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Recombinant human 14-3-3 epsilon was expressed in E. coli and purified by using conventional chromatography techniques.
    Alternative Names: FLJ45465 protein, epsilon polypeptide 14 3 3 E protein, 14/3/3 epsilon protein, Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide., MDCR protein, 14 3 3E protein, KCIP1 protein, YWHAE protein, MDS protein, 14.3.3 epsilon, Tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein protein, 14-3-3 epsilon protein, 14-3-3 epsilon protein, epsilon polypeptide protein, 14/3/3 epsilon, 14-3-3 epsilon, Protein kinase C inhibitor protein1 protein, Mitochondrial import stimulation factor L subunit protein, Tyrosine 3/tryptophan 5 -monooxygenase activation protein protein, KCIP-1 protein, KCIP 1 protein
    Molecular Weight
    29 kDa (255 AA)
    Pathways
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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