IL1RN Protein
-
- Target See all IL1RN Proteins
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
- Characteristics
-
Purified recombinant Human IL1 receptor antagonist protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
- Top Product
- Discover our top product IL1RN Protein
-
-
- Application Notes
- IL1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in PBS, pH 7.4.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
-
- Target
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Alternative Name
- IL1 receptor antagonist (IL1RN Products)
- Synonyms
- DIRA Protein, ICIL-1RA Protein, IL-1RN Protein, IL-1ra Protein, IL-1ra3 Protein, IL1F3 Protein, IL1RA Protein, IRAP Protein, MVCD4 Protein, IRAP1 Protein, IL1RN Protein, IL-1RA Protein, F630041P17Rik Protein, interleukin 1 receptor antagonist Protein, interleukin 1 receptor antagonist-like Protein, IL1RN Protein, Il1rn Protein, IL1RNL Protein
- Background
-
One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1 (IL-1), whose actions are regulated by the structurally related IL-1 receptor antagonist (IL-1 RA). IL-1 RA is a competitive IL-1 inhibitor and a powerful anti-inflammatory agent. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1 RA gene. Recombinant human IL-1 RA was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Anakinra protein, Interleukin-1 receptor antagonist protein, , IL1 inhibitor protein, IL-1, IL 1, IL1F3 protein, IL-1 protein, IL-1ra protein, ICIL-1RA protein, IL 1 protein, IL1, IL1RN protein, ICIL 1RA protein, Interleukin-1 receptor antagonist protein protein, ICIL1RA protein, IRAP protein, IL-1RN protein, IL1 inhibitor protein, IL1RA protein - Molecular Weight
- 17.2 kDa (153 AA)
- Pathways
- NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
-