CRYAA Protein

Catalog No. ABIN934883

Product Details

Target: CRYAA (Crystallin, alpha A (CRYAA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS

Characteristics: Purified recombinant Human CRYAA protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: CRYAA protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 50 mM NaCl, 0 mM EDTA.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: CRYAA (Crystallin, alpha A (CRYAA))

Alternative Name: CRYAA (CRYAA Products)

Synonyms: CRYA1 Protein, CTRCT9 Protein, HSPB4 Protein, AI323437 Protein, Acry-1 Protein, Crya-1 Protein, Crya1 Protein, DAcry-1 Protein, lop18 Protein, alpha-a-crystallin Protein, cryaa-A Protein, CRYAA Protein, wu:fc06h04 Protein, zgc:92036 Protein, HspB4 Protein, crystallin alpha A Protein, crystallin, alpha A Protein, alphaA-crystallin Protein, alpha-crystallin A chain-like Protein, crystallin alpha A S homeolog Protein, alpha-crystallin A chain Protein, CRYAA Protein, Cryaa Protein, CpipJ_CPIJ005646 Protein, cryaa Protein, LOC100384978 Protein, cryaa.S Protein, LOC458589 Protein, LOC102724652 Protein

Background: Alpha crystallins are composed of two gene products , alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell.
Alternative Names: Alpha-crystallin A chain protein, Crystallin Alpha 1 protein, Acry-1 protein, CRYAA protein, HSPB 4 protein, Crystallin alpha A protein, , HspB4 protein, CRYA 1 protein, Heat shock protein beta 4 protein, Zonular Central Nuclear Cataract protein, Alpha crystallin A chain protein, CRYA1 protein, Heat shock protein beta-4 protein

Molecular Weight: 19.9 kDa (173 AA)

Pathways: M Phase