alpha Synuclein E46K (active) Protein
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- Target
- alpha Synuclein E46K
- Protein Type
- Recombinant
- Protein Characteristics
- active
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKKGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
- Characteristics
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Purified recombinant Human alpha Synuclein E46 K protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
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- Application Notes
- Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0.1 M NaCl.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- alpha Synuclein E46K
- Background
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Alpha-synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate(E) to lysine(K). Recent studies have shown that this mutant(E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia(DLB). Alpha-synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques.
Alternative Names: Parkinson disease familial 1 protein, PD1 protein, Non-A4 component of amyloid precursor protein, alpha synuclein E46k protein, PD 1 protein, Alpha synuclein protein, alphaSYN protein, Non A beta component of AD amyloid protein, Non A4 component of amyloid precursor protein, Synuclein alpha protein, MGC110988 protein, alpha-synuclein e46k protein, MGC64356 protein, NACP protein, Non-A-beta component of alzheimers disease amyloid protein, precursor of PARK 1 protein, alpha-Synuclein protein, Non-A beta component of AD amyloid protein, MGC105443 protein, SNCA protein, MGC127560 protein, Alpha-synuclein isoform NACP140 protein, PARK4 protein, PARK1 protein, , PARK 4 protein - Molecular Weight
- 14.4 kDa (140 AA)
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