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alpha Synuclein E46K (active) Protein

Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Catalog No. ABIN934881
  • Target
    alpha Synuclein E46K
    Protein Type
    Recombinant
    Protein Characteristics
    active
    Origin
    Human
    Source
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Sequence
    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKKGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
    Characteristics
    Purified recombinant Human alpha Synuclein E46 K protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
    Purity
    > 95 % pure
  • Application Notes
    Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0.1 M NaCl.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
    Storage Comment
    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target
    alpha Synuclein E46K
    Background
    Alpha-synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate(E) to lysine(K). Recent studies have shown that this mutant(E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia(DLB). Alpha-synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques.
    Alternative Names: Parkinson disease familial 1 protein, PD1 protein, Non-A4 component of amyloid precursor protein, alpha synuclein E46k protein, PD 1 protein, Alpha synuclein protein, alphaSYN protein, Non A beta component of AD amyloid protein, Non A4 component of amyloid precursor protein, Synuclein alpha protein, MGC110988 protein, alpha-synuclein e46k protein, MGC64356 protein, NACP protein, Non-A-beta component of alzheimers disease amyloid protein, precursor of PARK 1 protein, alpha-Synuclein protein, Non-A beta component of AD amyloid protein, MGC105443 protein, SNCA protein, MGC127560 protein, Alpha-synuclein isoform NACP140 protein, PARK4 protein, PARK1 protein, , PARK 4 protein
    Molecular Weight
    14.4 kDa (140 AA)
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