SNCA Protein (active)

Catalog No. ABIN934871

Product Details

Target: SNCA (Synuclein, alpha (SNCA))

Protein Type: Recombinant

Protein Characteristics: active

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAP GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA

Characteristics: Purified recombinant Human alpha Synuclein A30 P protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid In 20 mM Tris-HCl buffer, pH 7.5, containing 0.1 M NaCl.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: alpha Synuclein A30P (SNCA Products)

Synonyms: snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein

Background: A Parkinson's disease-related point mutant (A30P) of alpha-synuclein. A30P mutant of alpha-synuclein was overexpressed in E. coli and the recombinant protein was purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques.
Alternative Names: alpha-Synuclein protein, MGC64356 protein, MGC110988 protein, SNCA protein, Synuclein alpha protein, Non-A4 component of amyloid precursor protein, MGC105443 protein, alphaSYN protein, Alpha-synuclein isoform NACP140 protein, Non A4 component of amyloid precursor protein, PARK4 protein, Non-A beta component of AD amyloid protein, PARK1 protein, NACP protein, PD1 protein, Non A beta component of AD amyloid protein, Parkinson disease familial 1 protein, , precursor of PARK 1 protein, PARK 4 protein, Non-A-beta component of alzheimers disease amyloid protein, MGC127560 protein, Alpha synuclein protein, PD 1 protein

Molecular Weight: 14.4 kDa (140 AA)

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity