SPARC Protein
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- Target See all SPARC Proteins
- SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
- Protein Type
- Native
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Osteonectin protein
Protein Source: Human platelets - Purity
- > 95 % pure
- Top Product
- Discover our top product SPARC Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Buffer
- 20 mM Tris, 150 M NaCl, pH 7.4.
- Precaution of Use
- Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C.
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- Target
- SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
- Alternative Name
- Osteonectin (SPARC Products)
- Synonyms
- ON Protein, AA517111 Protein, BM-40 Protein, hm:zeh0062 Protein, SPARC Protein, sparc Protein, secreted protein acidic and cysteine rich Protein, secreted acidic cysteine rich glycoprotein Protein, secreted protein, acidic, cysteine-rich (osteonectin) Protein, secreted protein, acidic, cysteine-rich (osteonectin) L homeolog Protein, secreted protein, acidic, cysteine-rich (osteonectin) S homeolog Protein, SPARC Protein, Sparc Protein, sparc Protein, sparc.L Protein, sparc.S Protein
- Background
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Osteonectin is an acidic, noncollagenous glycoprotein originally isolated from fetal and adult bovine bone matrix. In vitro bovine bone osteonectin binds type I collagen, calcium (kDa=3x10-7 M) and hydroxyapatite (kDa=8x10-8 M) and has been shown to be a potent inhibitor of hydroxyapatite seeded crystal growth. In this context it has been suggested that osteonectin may play an important role in the regulation of bone metabolism by binding hydroxyapatite to collagen.
Description: Human platelets. - Molecular Weight
- 32.7 kDa
- Pathways
- Autophagy
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