Tropomyosin Protein
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- Target See all Tropomyosin (TPM1) Proteins
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Protein Type
- Native
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Tropomyosin protein
Protein Source: Human cardiac tissue - Purity
- > 95 % pure
- Top Product
- Discover our top product TPM1 Protein
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Tropomyosin 1 (Alpha) (TPM1) (AA 91-188) protein (GST tag)
TPM1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) protein (GST tag)TPM1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 7) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Buffer
- 10 mM TRIS-HCl, pH 7.4, with 50 mM NaCl, 5 mM beta-mercaptoethanol and 5 mM EDTA.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Alternative Name
- Tropomyosin (TPM1 Products)
- Background
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Tropomyosin is an actin-binding protein that regulates actin mechanics. It is important, among other things, for muscle contraction. Tropomyosin, along with the troponin complex, associate with actin in muscle fibers and regulate muscle contraction by regulating the binding of myosin. In resting muscle, tropomyosin overlays the myosin binding sites on actin, with a single tropomyosin molecule spanning 7 actin subunits, and is locked down in this position by troponin T (tropomyosin binding troponin) and troponin I (inhibitory troponin).
Description: Human cardiac tissue. - Pathways
- Regulation of Actin Filament Polymerization
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