Factor VII Protein
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- Target See all Factor VII (F7) Proteins
- Factor VII (F7) (Coagulation Factor VII (F7))
- Protein Type
- Native
- Biological Activity
- Active
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Factor VII protein
Bioactivity: 3296 units/mg protein - Specific activity is determined by the Factor VII clotting assay. One unit of activity is equivalent to the factor VII activity in one milliliter of normal plasma.
Protein Source: Human serum/plasma - Purity
- > 95 % pure
- Top Product
- Discover our top product F7 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Buffer
- 50 % Glycerol/H2 O (vol/vol).
- Precaution of Use
- Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C.
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- Target
- Factor VII (F7) (Coagulation Factor VII (F7))
- Alternative Name
- Factor VII (F7 Products)
- Synonyms
- F7 Protein, wu:fb59f04 Protein, zgc:109870 Protein, SPCA Protein, AI114908 Protein, ATIII Protein, At-3 Protein, At3 Protein, LOC100223776 Protein, AI132620 Protein, Cf7 Protein, FVII Protein, mfVII Protein, f7 Protein, coagulation factor VII Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog Protein, F7 Protein, f7 Protein, Serpinc1 Protein, CpipJ_CPIJ009142 Protein, CpipJ_CPIJ010295 Protein, CpipJ_CPIJ020127 Protein, fa7 Protein, f7.S Protein
- Background
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Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.
Description: Human serum/plasma.
Alternative Names: Complement Factor VII - Molecular Weight
- 50 kDa
- Pathways
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
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