Complement Factor B Protein (CFB)

Catalog No. ABIN934807

Product Details

Target: Complement Factor B (CFB)

Protein Type: Native

Biological Activity: Active

Origin: Human

Source: Human

Characteristics: Purified native Human Complement Factor B
Bioactivity: 4, 700 U/mg - 100 % of factor B activity in NHS on a mg/mg basis
Protein Source: Human serum/plasma

Purity: > 98 % pure

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.2, no preservatives added,

Preservative: Without preservative

Precaution of Use: Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Aliquot and store at -70 °C or lower.

Target Details

Target: Complement Factor B (CFB)

Alternative Name: Complement Factor B (CFB Products)

Background: Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease.
Description: Human serum/plasma.
Alternative Names: Recombinant CFB

Molecular Weight: 93 kDa

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process