proBNP Protein
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- Target See all proBNP products
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Characteristics
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Purified recombinant Human ProBNP protein
Expression System: E.coli - Purification
- Immunoaffinity purification followed by ion exchange chromatography
- Purity
- > 95 % pure
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Buffer
- 10 mM KH2PO4, pH 7.4, 150 mM NaCl. No preservatives added. To prepare diluted samples of proBNP it is recommended to use buffer solutions containing carrier protein and detergent.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Aliquot and store at -70 °C or lower.
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- Target
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- Alternative Name
- ProBNP (proBNP Products)
- Synonyms
- BNP Protein, natriuretic peptide B Protein, NPPB Protein
- Background
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Brain natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The physiologic actions of BNP are similar to ANP and include decrease in systemic vascular resistance and central venous pressure as well as an increase in natriuresis. proBNP is the prohormone form of BNP.
Alternative Names: pro Brain Natriuretic Peptide Protein, NT-proBNP Protein, ProBNP, NPPB Protein
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