(1 reference)-
- Target See all Troponin I (TNNI) Proteins
- Troponin I (TNNI)
- Protein Type
- Native
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Troponin I protein (Cardiac)
Protein Source: Human cardiac tissue - Purity
- > 99 % pure
- Top Product
- Discover our top product TNNI Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as a liquid in 8 M Urea buffer with 30 mM NaCl, 50 mM Tris. HCl, 15 mM beta-mercaptoethanol, 1 mM EGTA, pH 8.0
- Precaution of Use
- Donor samples were tested and found to be negative for HBsAg, Anti-HIV-1/HIV-2, & HCV. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Store at -20 °C to -70 °C,
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: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." in: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).
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: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." in: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).
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- Target
- Troponin I (TNNI)
- Alternative Name
- Troponin I (TNNI Products)
- Background
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Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
Description: Human cardiac tissue.
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