IL16 Protein
(1 reference)-
- Target See all IL16 Proteins
- IL16 (Interleukin 16 (IL16))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
- Characteristics
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Purified recombinant Human IL16 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human CD4+ T lymphoytes using a concentration range of 1.0-100.0 ng/mL. - Purity
- > 97 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL16 Protein
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Interleukin 16 (IL16) (AA 1203-1332) (Active) protein (His tag)
IL16 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Interleukin 16 (IL16) (AA 1-454) protein (GST tag)IL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Lyophilized from 5 mM Na3PO4, pH 7.6.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).
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: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).
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- Target
- IL16 (Interleukin 16 (IL16))
- Alternative Name
- IL16 (IL16 Products)
- Synonyms
- IL16 Protein, LCF Protein, NIL16 Protein, PRIL16 Protein, prIL-16 Protein, mKIAA4048 Protein, IL-16 Protein, interleukin 16 Protein, IL16 Protein, Il16 Protein
- Background
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IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
Alternative Names: IL-16 protein, IL16, IL-16 protein, Interleukin 16 protein, IL 16, Lymphocyte Chemoattractant Factor protein, IL 16 protein, LCF protein, IL-16 - Molecular Weight
- 13.5 kDa
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