Caspase 4 Protein

Catalog No. ABIN925028

Product Details

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Positive Control (PC)

Characteristics: ~5,000 U/mg protein. One unit is defined as the amount of enzyme that cleaves 1 nmol of the caspase substrate WEHD-pNA per hour at 37°C in a reaction solution containing 50 mM HEPES, pH 7.2, 50 mM NaCl, 0.1% CHAPS, 10 mM EDTA, 5% glycerol and 10 mM DTT.

Purity: 95 % by SDS-PAGE

Application Details

Application Notes: Useful in screening caspase inhibitors, studying enzyme regulation and kinetics, determining target substrate or as a positive control in caspase activity assays. We recommend using 1 unit per assay for analyzing caspase activity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with PBS containing 15% glycerol to 1 U/µL.

Storage: -80 °C

Target Details

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Alternative Name: Caspase-4 (CASP4 Products)

Synonyms: ICE(rel)II Protein, ICEREL-II Protein, ICH-2 Protein, Mih1/TX Protein, TX Protein, Casp11 Protein, CASP13 Protein, CASP1 Protein, CASP4 Protein, Caspl Protein, ich-3 Protein, Casp4 Protein, caspase 4 Protein, caspase 4, apoptosis-related cysteine peptidase Protein, caspase-4 Protein, CASP4 Protein, Casp4 Protein, LOC100731032 Protein

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity