NK-1.1/CD161c Protein (AA 1-223) (His tag)
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- Target See all NK-1.1/CD161c products
- NK-1.1/CD161c (NK-1.1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-223
- Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NK-1.1/CD161c protein is labelled with His tag.
- Purpose
- Custom-made recombinant Klrb1c Protein expressed in mammalian cells.
- Sequence
- MDTASIYLGL KPPRTLGAWH ESPPSLPPDA CRCPRSHRLA LKLSCAGLIL LVLTLIGMSV LVRVLVQKPS REKCCVFIQE NLNKTTDCSV NLECPQDWLL HRDKCFHVSQ VSNTWEEGQA DCGRKGATLL LIQDQEELRF LLDSIKEKYN SFWIGLRFTL PDMNWKWING TTFNSDVLKI TGVTENGSCA SILGDKVTPE SCASDNRWIC QKELNHETPS NDS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- NK-1.1/CD161c (NK-1.1)
- Alternative Name
- Klrb1c (NK-1.1/CD161c Products)
- Background
- Killer cell lectin-like receptor subfamily B member 1C (CD161 antigen-like family member C) (Lymphocyte antigen 55c) (Ly-55c) (NK1.1) (NKR-P1.9) (NKR-P1C) (Natural killer cell surface protein P1-40) (NKR-P1 40) (CD antigen CD161c),FUNCTION: Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. {ECO:0000269|PubMed:12813047, ECO:0000269|PubMed:15814704}.
- Molecular Weight
- 25.1 kDa
- UniProt
- P27814
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