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ARPIN Protein (AA 1-226) (His tag)

custom-made Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7560823
  • Target See all ARPIN Proteins
    ARPIN
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-226
    Origin
    • 3
    • 1
    • 1
    • 1
    Mouse
    Source
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This ARPIN protein is labelled with His tag.
    Purpose
    Custom-made recombinant Arpin Protein expressed in mammalian cells.
    Sequence
    MSRIYQDSAL RNKAVQSARL PGTWDPATHQ GGNGILLEGE LVDVSRHSIL DAHGRKERYY VLYIQPSCIH RRKFDPKGNE IEPNFSATRK VNTGFLMSSY KVEAKGDTDR LTLEALKSLV NKPQLLELTE SLTPDQAVAF WMPESEMEVM ELELGTGVRL KTRGDGPFID SLAKLELGTV TKCNFAGDGK TGASWTDNIM AQKSSERNTA EIREQGDGAE DEEWDD Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    Specificity
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    Characteristics
    Key Benefits:
    • Made to order protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    Purity
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    Grade
    custom-made
    Top Product
    Discover our top product ARPIN Protein
  • Application Notes
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    The buffer composition is at the discretion of the manufacturer.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C.
    Expiry Date
    12 months
  • Target
    ARPIN
    Abstract
    ARPIN Products
    Background
    Arpin (Arp2/3 inhibition protein),FUNCTION: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competitive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence (By similarity). {ECO:0000250}.
    Molecular Weight
    25.2 kDa
    UniProt
    Q9D0A3
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