CNTNAP2 Protein (MYC tag)

Catalog No. ABIN7538799

Product Details

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Protein Type: cVLP

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CNTNAP2 protein is labelled with MYC tag.

Application: Western Blotting (WB), ELISA

Purpose: Chimeric VLP of HIV (Gag/Pol) CASPR2

Characteristics: Chimeric Gag/Pol virus-like particles (cVLP) were produced in HEK cells by co-expression of the HIV-1 Gag/Pol polyprotein with a membrane bound target protein. The VLPs do not contain the viral genome, cannot replicate and are not infectious.

Purification: Polyethylene glycol precipitation

Biological Activity Comment: active

Application Details

Application Notes: Applications: Immunogenic antigen, antigen for ELISA and Western blot.
Western blot: 1-10 μg, ELISA: 1-5 μg/mL

Comment:

Virus-like Particles are multiprotein complexes that resemble a native virus, but lack the genetic information. Therefore, VLPs are safe to handle in numerous fields of applications. For example, VLPs can be applied as antigen in serological assays (e.g. ELISA), or serve as reference material to standardize the performance of different diagnostic tests (e.g. rapid antigen tests or ELISA). Due to the self-adjuvanting properties of VLPs is the most common application of VLPs the use as antigen for immunizations for vaccine development or antibody discovery campaigns.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Storage: -80 °C

Storage Comment: - 80°C

Target Details

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Alternative Name: CNTNAP2 / CASPR2 (CNTNAP2 Products)

Synonyms: AUTS15 Protein, CASPR2 Protein, CDFE Protein, NRXN4 Protein, PTHSL1 Protein, 5430425M22Rik Protein, Caspr2 Protein, mKIAA0868 Protein, CASPR Protein, MGC145769 Protein, MGC147944 Protein, MGC147981 Protein, contactin associated protein like 2 Protein, contactin associated protein-like 2 Protein, contactin associated protein like 2b Protein, CNTNAP2 Protein, Cntnap2 Protein, cntnap2b Protein, cntnap2 Protein

Background: CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C omain,discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. HIV (Human Immunodeficiency Virus) is a retrovirus (genus: Lentivirus, family: Retroviridae) that was identified as the cause of AIDS (Acquired Immunodeficiency Syndrome) in the early 1980s.