TADA2B Protein

Catalog No. ABIN7538563

Product Details

Target: TADA2B (Transcriptional Adaptor 2B (TADA2B))

Protein Type: Synthetic Nanodisc

Origin: Human

Source: Mammalian Cells

Purpose: Human ADA2B full length protein-synthetic nanodisc

Characteristics: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Application Details

Comment:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TADA2B (Transcriptional Adaptor 2B (TADA2B))

Alternative Name: ADA2B (TADA2B Products)

Synonyms: ADA2B Protein, RGD1561605 Protein, AA474455 Protein, Gm145 Protein, MGC84576 Protein, TADA2B Protein, DKFZp469I1816 Protein, wu:fb72h11 Protein, wu:fi12b07 Protein, wu:fi33a06 Protein, zgc:110397 Protein, ADA2(beta) Protein, transcriptional adaptor 2B Protein, transcriptional adaptor 2B L homeolog Protein, transcriptional adaptor 2B pseudogene Protein, Tada2b Protein, TADA2B Protein, tada2b.L Protein, LOC526838 Protein, tada2b Protein

Background: This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014]

Molecular Weight: The human full length ADA2B protein has a MW of 50kDa

UniProt: P18089

Pathways: Chromatin Binding