TAAR1 Protein

Catalog No. ABIN7538556

Product Details

Target: TAAR1 (Trace Amine Associated Receptor 1 (TAAR1))

Protein Type: Synthetic Nanodisc

Origin: Human

Source: Mammalian Cells

Purpose: Human TAAR1 full length protein-synthetic nanodisc

Characteristics: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Application Details

Comment:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TAAR1 (Trace Amine Associated Receptor 1 (TAAR1))

Alternative Name: TAAR1 (TAAR1 Products)

Synonyms: RP11-295F4.9 Protein, TA1 Protein, TAR1 Protein, TRAR1 Protein, Tar1 Protein, Trar1 Protein, taR-1 Protein, si:dkey-7c18.14 Protein, trace amine associated receptor 1 Protein, trace amine-associated receptor 1 Protein, trace-amine-associated receptor 1 Protein, trace amine associated receptor 1b Protein, TAAR1 Protein, Taar1 Protein, taar1b Protein

Background: The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopamine, and tryptamine. While primarily functioning in neurologic systems, there is evidence that this gene is involved in blood cell and immunologic functions as well. This gene is thought to be intronless. [provided by RefSeq, Nov 2015]

Molecular Weight: The human full length TAAR1 protein has a MW of 39.1kDa

UniProt: Q96RJ0