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TAS1R3 Protein

TAS1R3 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538545
  • Target See all TAS1R3 Proteins
    TAS1R3 (Taste Receptor, Type 1, Member 3 (TAS1R3))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 2
    • 2
    Human
    Source
    • 4
    Mammalian Cells
    Purpose
    Human TAS1R3 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    TAS1R3 (Taste Receptor, Type 1, Member 3 (TAS1R3))
    Alternative Name
    TAS1R3 (TAS1R3 Products)
    Synonyms
    tas1r3 Protein, T1R3 Protein, Sac Protein, T1r3 Protein, taste receptor, type 1, member 3 Protein, taste 1 receptor member 3 Protein, TAS1R3 Protein, tas1r3 Protein, Tas1r3 Protein
    Background
    The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response.
    Molecular Weight
    The human full length TAS1R3 protein has a MW of 93.4 kDa
    UniProt
    Q7RTX0
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