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S1PR4 Protein

S1PR4 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538536
  • Target See all S1PR4 Proteins
    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 2
    Mammalian Cells
    Purpose
    Human S1PR4 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product S1PR4 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
    Alternative Name
    S1PR4 (S1PR4 Products)
    Synonyms
    EDG6 Protein, edg6 Protein, LPC1 Protein, S1P4 Protein, SLP4 Protein, Edg6 Protein, Lpc1 Protein, S1p4 Protein, sphingosine-1-phosphate receptor 4 Protein, sphingosine-1-phosphate receptor 4 S homeolog Protein, S1PR4 Protein, s1pr4.S Protein, S1pr4 Protein
    Background
    This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]
    Molecular Weight
    The human full length S1PR4 protein has a MW of 41.6kDa
    UniProt
    O95977
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