S1PR2 Protein
S1PR2
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all S1PR2 Proteins
- S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human S1PR2 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Sphingosine-1-Phosphate Receptor 2 (S1PR2) protein (Myc-DYKDDDDK Tag)
S1PR2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))
- Alternative Name
- S1PR2 (S1PR2 Products)
- Synonyms
- AGR16 Protein, EDG-5 Protein, EDG5 Protein, Gpcr13 Protein, H218 Protein, LPB2 Protein, S1P2 Protein, 1100001A16Rik Protein, Edg5 Protein, LPb2 Protein, GPCR18 Protein, snGPCR18 Protein, sphingosine-1-phosphate receptor 2 Protein, S1PR2 Protein, S1pr2 Protein
- Background
- This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]
- Molecular Weight
- The human full length S1PR2 protein has a MW of 38.9kDa
- UniProt
- O95136
- Pathways
- Synaptic Membrane
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