SELPLG Protein (AA 34-356) (His tag)
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- Target See all SELPLG Proteins
- SELPLG (Selectin P Ligand (SELPLG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 34-356
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Origin
- Cynomolgus
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This SELPLG protein is labelled with His tag.
- Purpose
- Recombinant Cynomolgus SELPLG protein with C-terminal 6xHis tag
- Specificity
- SELPLG (Leu34-Cys356) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SELPLG Protein
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Selectin P Ligand (SELPLG) (AA 34-356) protein (His tag)
SELPLG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P Ligand (SELPLG) (AA 42-307) protein (His tag)SELPLG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P Ligand (SELPLG) (AA 42-320) protein (His tag)SELPLG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Selectin P Ligand (SELPLG) (AA 18-320) protein (His tag)SELPLG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin P Ligand (SELPLG) protein (Fc Tag)SELPLG Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- SELPLG (Selectin P Ligand (SELPLG))
- Alternative Name
- SELPLG (SELPLG Products)
- Synonyms
- CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein
- Background
- This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
- Molecular Weight
- predicted molecular mass of 34.3 kDa after removal of the signal peptide.
- UniProt
- A0A7N9CVJ8
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