RXFP2 Protein
RXFP2
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all RXFP2 Proteins
- RXFP2 (Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human RXFP2 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product RXFP2 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- RXFP2 (Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2))
- Alternative Name
- RXFP2 (RXFP2 Products)
- Synonyms
- GPR106 Protein, GREAT Protein, INSL3R Protein, LGR8 Protein, LGR8.1 Protein, RXFPR2 Protein, Gpcr Protein, Lgr8 Protein, Gpr106 Protein, Great Protein, lgr8.1 Protein, rxfp2 Protein, rxfp2b Protein, zgc:63668 Protein, relaxin/insulin like family peptide receptor 2 Protein, relaxin/insulin-like family peptide receptor 2 Protein, relaxin/insulin-like family peptide receptor 2a Protein, RXFP2 Protein, Rxfp2 Protein, rxfp2a Protein
- Background
- This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
- Molecular Weight
- The human full length RXFP2 protein has a MW of 86.5kDa
- UniProt
- Q8WXD0
- Pathways
- cAMP Metabolic Process, Myometrial Relaxation and Contraction
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