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P2RY2 Protein

P2RY2 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538499
  • Target See all P2RY2 Proteins
    P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 5
    • 3
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    Mammalian Cells
    Purpose
    Human P2RY2 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product P2RY2 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))
    Alternative Name
    P2RY2 (P2RY2 Products)
    Synonyms
    P2U1 Protein, P2Y2 Protein, HP2U Protein, P2RU1 Protein, P2U Protein, P2UR Protein, P2Y2R Protein, P2Y purinoceptor 2 Protein, purinergic receptor P2Y, G-protein coupled 2 Protein, purinergic receptor P2Y2 Protein, p2ry2 Protein, P2ry2 Protein, P2RY2 Protein
    Background
    The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]
    Molecular Weight
    The human full length P2RY2 protein has a MW of 42.3kDa
    UniProt
    P41231
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Smooth Muscle Cell Migration
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