P2RY10 Protein

Catalog No. ABIN7538494

Product Details

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Protein Type: Synthetic Nanodisc

Origin: Human

Source: Mammalian Cells

Purpose: Human P2Y10 full length protein-synthetic nanodisc

Characteristics: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Application Details

Comment:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Alternative Name: P2Y10 (P2RY10 Products)

Synonyms: 5830408N17Rik Protein, P2Y10 Protein, RGD1561912 Protein, purinergic receptor P2Y, G-protein coupled, 10 Protein, P2Y receptor family member 10 Protein, purinergic receptor P2Y, G-protein coupled, 10 L homeolog Protein, putative P2Y purinoceptor 10 Protein, purinergic receptor P2Y, G-protein coupled 10 Protein, purinergic receptor P2Y10 Protein, P2RY10 Protein, p2ry10.L Protein, LOC100396399 Protein, P2ry10 Protein

Background: The protein encoded by this gene belongs to the family of G-protein coupled receptors that are preferentially activated by adenosine and uridine nucleotides. There is a pseudogene for this gene nearby on chromosome X. Multiple alternatively spliced transcripts have been observed. [provided by RefSeq, Apr 2016]

Molecular Weight: The human full length P2Y10 protein has a MW of 38.8kDa

UniProt: O00398