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P2RY1 Protein

P2RY1 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538493
  • Target See all P2RY1 Proteins
    P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 5
    • 2
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    Mammalian Cells
    Purpose
    Human P2RY1 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product P2RY1 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))
    Alternative Name
    P2RY1 (P2RY1 Products)
    Synonyms
    P2Y1 Protein, P2y Protein, P2y1 Protein, purinergic receptor P2Y, G-protein coupled 1 Protein, purinergic receptor P2Y1 Protein, P2ry1 Protein, P2RY1 Protein
    Background
    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
    Molecular Weight
    The human full length P2RY1 protein has a MW of 42.1kDa
    UniProt
    P47900
    Pathways
    Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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