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PTGDR Protein

PTGDR Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538489
  • Target See all PTGDR Proteins
    PTGDR (Prostaglandin D2 Receptor (PTGDR))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 2
    Mammalian Cells
    Purpose
    Human PD2R full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product PTGDR Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    PTGDR (Prostaglandin D2 Receptor (PTGDR))
    Alternative Name
    PD2R (PTGDR Products)
    Synonyms
    AS1 Protein, ASRT1 Protein, DP Protein, DP1 Protein, PTGDR1 Protein, Ptgdr Protein, Ptgdr2 Protein, PTGDR Protein, PGD Protein, prostaglandin D2 receptor Protein, prostaglandin D receptor Protein, PTGDR Protein, Ptgdrl Protein, Ptgdr Protein
    Background
    This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
    Molecular Weight
    The human full length PD2R protein has a MW of 40.3kDa
    UniProt
    Q13258
    Pathways
    Thromboxane A2 Receptor Signaling
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