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Oxytocin Receptor Protein (OXTR)

OXTR Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538467
  • Target See all Oxytocin Receptor (OXTR) Proteins
    Oxytocin Receptor (OXTR)
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 3
    • 1
    Human
    Source
    • 5
    • 2
    Mammalian Cells
    Purpose
    Human OXYR full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product OXTR Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Oxytocin Receptor (OXTR)
    Alternative Name
    OXYR (OXTR Products)
    Synonyms
    OXTR Protein, OT-R Protein, OTR Protein, OTR1 Protein, oxytocin receptor Protein, OXTR Protein, Oxtr Protein
    Background
    The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
    Molecular Weight
    The human full length OXYR protein has a MW of 42.8kDa
    UniProt
    P30559
    Pathways
    Myometrial Relaxation and Contraction, Feeding Behaviour
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