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OXER1 Protein

OXER1 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538465
  • Target See all OXER1 Proteins
    OXER1 (Oxoeicosanoid Receptor 1 (OXER1))
    Protein Type
    Synthetic Nanodisc
    Origin
    Human
    Source
    • 2
    Mammalian Cells
    Purpose
    Human OXER1 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product OXER1 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    OXER1 (Oxoeicosanoid Receptor 1 (OXER1))
    Alternative Name
    OXER1 (OXER1 Products)
    Synonyms
    GPCR Protein, GPR170 Protein, TG1019 Protein, oxoeicosanoid receptor 1 Protein, OXER1 Protein
    Background
    Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length OXER1 protein has a MW of 45.8kDa
    UniProt
    Q8TDS5
    Pathways
    cAMP Metabolic Process
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