OSCAR Protein (AA 19-282) (His tag)
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- Target See all OSCAR Proteins
- OSCAR (Osteoclast Associated Receptor (OSCAR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-282
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This OSCAR protein is labelled with His tag.
- Purpose
- Recombinant human OSCAR Protein with C-terminal 6xHis tag
- Specificity
- OSCAR (Asp19-Val282) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product OSCAR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- OSCAR (Osteoclast Associated Receptor (OSCAR))
- Alternative Name
- OSCAR (OSCAR Products)
- Synonyms
- OSCAR Protein, mOSCAR-M3 Protein, mOSCAR Protein, mOSCAR-M1 Protein, mOSCAR-M2 Protein, PIGR3 Protein, PIgR-3 Protein, RGD1559897 Protein, osteoclast associated, immunoglobulin-like receptor Protein, osteoclast-associated immunoglobulin-like receptor Protein, osteoclast associated receptor Protein, OSCAR Protein, LOC748876 Protein, Oscar Protein
- Background
- Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
- Molecular Weight
- predicted molecular mass of 29.2 kDa after removal of the signal peptide. The apparent molecular mass of OSCAR-His is 35-55 kDa due to glycosylation.
- UniProt
- Q8IYS5
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