OPN5 Protein
OPN5
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all OPN5 Proteins
- OPN5 (Opsin 5 (OPN5))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human OPN5 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product OPN5 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- OPN5 (Opsin 5 (OPN5))
- Alternative Name
- OPN5 (OPN5 Products)
- Synonyms
- cOpn5L2 Protein, opsin-5 Protein, si:ch211-105n9.2 Protein, neuropsin Protein, GPR136 Protein, PGR12 Protein, TMEM13 Protein, Gpr136 Protein, Neuropsin Protein, opsin 5 Protein, opsin 5 L homeolog Protein, OPN5 Protein, opn5 Protein, opn5.L Protein, Opn5 Protein
- Background
- Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- Molecular Weight
- The human full length OPN5 protein has a MW of 39.7kDa
- UniProt
- Q6U736
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