OPN3 Protein
OPN3
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all OPN3 products
- OPN3 (Opsin 3 (OPN3))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human OPN3 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- OPN3 (Opsin 3 (OPN3))
- Alternative Name
- OPN3 (OPN3 Products)
- Synonyms
- OPN3 Protein, ECPN Protein, ERO Protein, Ecpn Protein, panopsin Protein, opsin 3 Protein, opn3 Protein, OPN3 Protein, Opn3 Protein
- Background
- Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]
- Molecular Weight
- The human full length OPN3 protein has a MW of 44.9kDa
- UniProt
- Q9H1Y3
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