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O3FAR1 Protein

O3FAR1 Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538454
  • Target See all O3FAR1 Proteins
    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 3
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    Mammalian Cells
    Purpose
    Human FFAR4 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product O3FAR1 Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
    Alternative Name
    FFAR4 (O3FAR1 Products)
    Synonyms
    BMIQ10 Protein, GPR120 Protein, GPR129 Protein, GT01 Protein, O3FAR1 Protein, PGR4 Protein, AI552415 Protein, Gpr120 Protein, Gpr129 Protein, KPG_013 Protein, O3far1 Protein, Pgr4 Protein, free fatty acid receptor 4 Protein, phosphodiesterase 6C Protein, FFAR4 Protein, Ffar4 Protein, PDE6C Protein
    Background
    This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
    Molecular Weight
    The human full length FFAR4 protein has a MW of 40.5kDa
    UniProt
    Q5NUL3
    Pathways
    Hormone Transport
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