O3FAR1 Protein
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- Target See all O3FAR1 Proteins
- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human FFAR4 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product O3FAR1 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
- Alternative Name
- FFAR4 (O3FAR1 Products)
- Synonyms
- BMIQ10 Protein, GPR120 Protein, GPR129 Protein, GT01 Protein, O3FAR1 Protein, PGR4 Protein, AI552415 Protein, Gpr120 Protein, Gpr129 Protein, KPG_013 Protein, O3far1 Protein, Pgr4 Protein, free fatty acid receptor 4 Protein, phosphodiesterase 6C Protein, FFAR4 Protein, Ffar4 Protein, PDE6C Protein
- Background
- This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
- Molecular Weight
- The human full length FFAR4 protein has a MW of 40.5kDa
- UniProt
- Q5NUL3
- Pathways
- Hormone Transport
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