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NPY2R Protein

NPY2R Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538409
  • Target See all NPY2R Proteins
    NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 5
    • 3
    • 2
    Human
    Source
    • 6
    • 2
    • 2
    Mammalian Cells
    Purpose
    Human NPY2R full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product NPY2R Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))
    Alternative Name
    NPY2R (NPY2R Products)
    Synonyms
    NPY2-R Protein, npy2r Protein, si:dkey-30k22.9 Protein, NPY-Y2 Protein, neuropeptide Y receptor Y2 Protein, NPY2R Protein, npy2r Protein, Npy2r Protein
    Background
    Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    The human full length NPY2R protein has a MW of 42.7kDa
    UniProt
    P49146
    Pathways
    cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour
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