NPY2R Protein
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- Target See all NPY2R Proteins
- NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human NPY2R full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product NPY2R Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))
- Alternative Name
- NPY2R (NPY2R Products)
- Synonyms
- NPY2-R Protein, npy2r Protein, si:dkey-30k22.9 Protein, NPY-Y2 Protein, neuropeptide Y receptor Y2 Protein, NPY2R Protein, npy2r Protein, Npy2r Protein
- Background
- Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length NPY2R protein has a MW of 42.7kDa
- UniProt
- P49146
- Pathways
- cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour
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