NPFFR2 Protein
NPFF2
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all NPFFR2 (NPFF2) Proteins
- NPFFR2 (NPFF2) (Neuropeptide FF Receptor 2 (NPFF2))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human NPFF2 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product NPFF2 Protein
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Neuropeptide FF Receptor 2 (NPFF2) (AA 1-420), (full length) protein (His tag)
NPFF2 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- NPFFR2 (NPFF2) (Neuropeptide FF Receptor 2 (NPFF2))
- Alternative Name
- NPFF2 (NPFF2 Products)
- Synonyms
- GPR74 Protein, HLWAR77 Protein, NPFF2 Protein, NPGPR Protein, Gpr74 Protein, HG31 Protein, Npff2 Protein, Npgpr Protein, neuropeptide FF receptor 2 Protein, NPFFR2 Protein, Npffr2 Protein
- Background
- This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
- Molecular Weight
- The human full length NPFF2 protein has a MW of 60.3kDa
- UniProt
- Q9Y5X5
- Pathways
- cAMP Metabolic Process
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