NPFFR1 Protein
NPFFR1
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all NPFFR1 products
- NPFFR1 (Neuropeptide FF Receptor 1 (NPFFR1))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human NPFF1 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- NPFFR1 (Neuropeptide FF Receptor 1 (NPFFR1))
- Alternative Name
- NPFF1 (NPFFR1 Products)
- Synonyms
- GPR147 Protein, NPFF1 Protein, NPFF1R1 Protein, OT7T022 Protein, Gm236 Protein, Gpr147 Protein, RFRPR Protein, MGC83178 Protein, NPFFR1 Protein, LOC100230250 Protein, neuropeptide FF receptor 1 Protein, neuropeptide FF receptor 1 L homeolog Protein, inorganic pyrophosphatase-like Protein, NPFFR1 Protein, Npffr1 Protein, npffr1.L Protein, LOC100230250 Protein
- Background
- Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length NPFF1 protein has a MW of 47.8kDa
- UniProt
- Q9GZQ6
- Pathways
- cAMP Metabolic Process
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