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MADCAM1 Protein (AA 19-317) (His tag)

MADCAM1 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7538397
  • Target See all MADCAM1 Proteins
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-317
    Origin
    • 10
    • 4
    • 1
    Human
    Source
    • 8
    • 4
    • 2
    • 1
    Mammalian Cells
    Purification tag / Conjugate
    This MADCAM1 protein is labelled with His tag.
    Purpose
    Recombinant human MADCAM1 Protein with C-terminal 6xHis tag
    Specificity
    MADCAM1 (Gln19-Gln317) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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    Discover our top product MADCAM1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    Alternative Name
    MADCAM1 (MADCAM1 Products)
    Synonyms
    MACAM1 Protein, AV211525 Protein, mucosal vascular addressin cell adhesion molecule 1 Protein, MADCAM1 Protein, Madcam1 Protein
    Background
    The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 32.2 kDa after removal of the signal peptide.
    UniProt
    Q13477
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