Motilin Receptor Protein (MLNR)
MLNR
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all Motilin Receptor (MLNR) products
- Motilin Receptor (MLNR)
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human MTLR full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Motilin Receptor (MLNR)
- Alternative Name
- MTLR (MLNR Products)
- Synonyms
- GPR38 Protein, MTLR1 Protein, MLNR Protein, LOC100101581 Protein, motilin receptor Protein, MLNR Protein
- Background
- Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a motilin receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]
- Molecular Weight
- The human full length MTLR protein has a MW of 45.3kDa
- UniProt
- O43193
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