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Melatonin Receptor 1B Protein (MTNR1B)

MTNR1B Origin: Human Host: Mammalian Cells Synthetic Nanodisc
Catalog No. ABIN7538389
  • Target See all Melatonin Receptor 1B (MTNR1B) Proteins
    Melatonin Receptor 1B (MTNR1B)
    Protein Type
    Synthetic Nanodisc
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    Mammalian Cells
    Purpose
    Human MTR1B full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product MTNR1B Protein
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Melatonin Receptor 1B (MTNR1B)
    Alternative Name
    MTR1B (MTNR1B Products)
    Synonyms
    FGQTL2 Protein, MEL-1B-R Protein, MT2 Protein, Mel1b-r Protein, Mel-1B-R Protein, MTNR1B Protein, mtnr1br Protein, MEL1B Protein, Mel1b Protein, Mt2 Protein, mel1b Protein, mtnr1b Protein, melatonin receptor 1B Protein, melatonin receptor type 1C S homeolog Protein, melatonin receptor type 1Ba Protein, MTNR1B Protein, Mtnr1b Protein, mtnr1c.S Protein, mtnr1bb Protein, mtnr1ba Protein
    Background
    This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
    Molecular Weight
    The human full length MTR1B protein has a MW of 40.2kDa
    UniProt
    P49286
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