MC5 Receptor Protein
MC5R
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all MC5 Receptor (MC5R) Proteins
- MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human MC5R full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product MC5R Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))
- Alternative Name
- MC5R (MC5R Products)
- Synonyms
- MC2 Protein, MC5R Protein, MC5 Protein, mc5br Protein, mc5ra Protein, zMC5b Protein, zgc:194217 Protein, mc5ar Protein, mc5rb Protein, zMC5a Protein, melanocortin 5 receptor Protein, melanocortin 5b receptor Protein, melanocortin 5a receptor Protein, MC5R Protein, Mc5r Protein, mc5r Protein, mc5rb Protein, mc5ra Protein
- Background
- This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010]
- Molecular Weight
- The human full length MC5R protein has a MW of 36.6kDa
- UniProt
- P33032
- Pathways
- cAMP Metabolic Process
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