MCHR2 Protein
MCHR2
Origin: Human
Host: Mammalian Cells
Synthetic Nanodisc
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- Target See all MCHR2 products
- MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- Mammalian Cells
- Purpose
- Human MCHR2 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))
- Alternative Name
- MCHR2 (MCHR2 Products)
- Synonyms
- GPR145 Protein, GPRv17 Protein, MCH-2R Protein, MCH-R2 Protein, MCH2 Protein, MCH2R Protein, MCHR-2 Protein, SLT Protein, melanin concentrating hormone receptor 2 Protein, MCHR2 Protein
- Background
- Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length MCHR2 protein has a MW of 38.8kDa
- UniProt
- Q969V1
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