MRGPRX3 Protein

Catalog No. ABIN7538374

Product Details

Target: MRGPRX3 (MAS-Related GPR, Member X3 (MRGPRX3))

Protein Type: Synthetic Nanodisc

Origin: Human

Source: Mammalian Cells

Purpose: Human MRGX3 full length protein-synthetic nanodisc

Characteristics: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Application Details

Comment:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: MRGPRX3 (MAS-Related GPR, Member X3 (MRGPRX3))

Alternative Name: MRGX3 (MRGPRX3 Products)

Synonyms: Gm660 Protein, Mrgprx3 Protein, GPCR Protein, MRGX3 Protein, SNSR1 Protein, SNSR2 Protein, MrgA Protein, Mrga10 Protein, Mrgpra Protein, MAS-related GPR, member X3, pseudogene Protein, MAS related GPR family member X3 Protein, mas-related G-protein coupled receptor member X2-like Protein, MAS-related GPR, member X3 Protein, Mrgprx3-ps Protein, MRGPRX3 Protein, LOC100359273 Protein, Mrgprx3 Protein

Background: This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009]

Molecular Weight: The human full length MRGX3 protein has a MW of 36.5kDa

UniProt: Q96LB0